CENTER ON BEHAVIORAL MEDICINE
BEHAVIORAL GENETICSBehavioral Genetics: Research Article
Pillare, R. C., Bailey, J.M. (1998) Human Sexual Orientation Has a
Component. Human Biology; Apr 1998; 70, 2; Research Library
ABSTRACT: We present an overview of behavioral genetics research on homosexual and heterosexual orientation. Family, twin, and adoptee studies indicate that homosexuality and thus heterosexuality run in families. Sibling, twin, and adoptee concordance rates are compatible with the hypothesis that genes account for at least half of the variance in sexual orientation. We note observations of homosexual behavior in animal species, but the analogy to human sexual orientation is unclear. We discuss the reproductive disadvantage of a homosexual orientation and present possible mechanisms that could maintain a balanced polymorphism in human populations.
Abramson, P., and S.D. Pinkerton. 1996. Electrons and sex. Science 273:1155-1156.
Bailey, J.M., and A.P. Bell. 1993. Familiality of female and male homosexuality. Behav. Genet. 23:313-322.
Bailey, J.M., and D. Benishay. 1993. Familial aggregation of female sexual orientation. Am. J. Psychiatr. 150:272-277.
Bailey, J.M., and R.C. Pillard. 1991. A genetic study of male sexual orientation. Arch. Gen. Pssrh iatr. 48:1089-1096.
Bailey, J.M., and K.J. Zucker. 1995. Childhood sex-typed behavior and sexual orientation: A conceptual analysis and quantitative review. Devel. Psychol. 31:43-55.
Bailey, J.M., M.P. Dunne, and N.G. Martin. 1996. Distribution correlates and determinants of sexual orientation in a national twin sample. Unpublished.
Bailey, J.M., J. Miller, and L. Willerman. 1993. Maternally rated childhood gender nonconformity in homosexuals and heterosexuals. Arch. Sex. Behav. 22:461-469.
Bailey, J.M., J. Nothnagel, and M. Wolfe. 1995. Retrospectively measured individual differences in childhood sex-typed behavior among gay men: Correspondence between self-and maternal reports. Arch. Sex. Behav. 24:613-622.
Bailey, J.M., L. Willerman, and C. Parks. 1991. A test of the maternal stress hypothesis of human male homosexuality. Arch. Sex. Behav. 20:277-293.
Bailey, J.M., R.L. Murphy, S. Ferrando et al. 1995. Siblings of a systematically ascertained cohort of HIV-infected homosexual men. Unpublished.
Bailey, J.M., R.C. Pillard, M.C. Neale et al. 1993. Heritable factors influence sexual orientation in women. Arch. Gen. Psychiatr. 50:217-223.
Bell, A.P., M.S. Weinberg, and S.K. Hammersmith. 1981. Sexual Preference: Its Development in Men and Women. Bloomington, IN: Indiana University Press.
Bern, D.J. 1996. Exotic becomes erotic: A developmental theory of sexual orientation. Psychol. Rev. 103:320-335.
Blanchard, R., and A.F. Bogaert. 1996. Homosexuality in men and number of older brothers. Am. J. Psychiatr. 153:27-31.
Bogaert, A.F. 1996. Volunteer bias in human sexuality research: Evidence for both sexuality and personality differences in males. Arch. Sex. Behav. 25:125-140.
Bogaert, A.F., and R. Blanchard. 1996. Handedness in homosexual and heterosexual men in the Kinsey interview data. Arch. Sex. Behav. 25:373-378.
Buhrich, N.J., J.M. Bailey, and N.G. Martin. 1991. Sexual orientation, sexual identity, and sex-dimorphic behaviors in male twins. Behav. Genet. 21:75-96.
Catania, J.A., D. Binson, A. van der Straten et al. 1995. Methodological research on sexual behavior in the AIDS era. In Annual Review of Sex Research: An Integrative and Interdisciplinarv Review, R.C. Rosen, ed. Mount Vernon, IA: Society for the Scientific Study of Sexuality, 77-125.
Chevalier-Skolnikoff, S. 1976. Homosexual behavior in a laboratory group of stumptail monkeys (Maca ar-ctoides): Forms, contexts, and possible social functions. Arch. Sex. Behav. 5:511-527.
Diamond, M. 1993. Homosexuality
in different populations. Arch. Sex. Behav. 32:291-310.
Eckert, E.D., T.J. Bouchard, J. Bohlen et al. 1986. Homosexuality in monozygotic twins reared apart. Br. J. Psychiatr. 148:421-425.
Fausto-Sterling, A. 1995. Animal models for the development of human sexuality: A critical evaluation. J. Homosex. 28:217-236.
Fisher. R.A. 1922. On the dominance ratio. Proc. R. Soc. Edinburgh 42:321-341.
Fox, R.C. 1996. Bisexuality: An
of theory and research. In Textbook of Homosex-
Fridell, S.R., K.J. Zucker, S.J. Bradley et al. 1996. Physical attractiveness of girls with gender identity disorder. Arch. Sex. Behav. 25:17-31.
Gebhard, P. 1972. Incidence of overt homosexuality in the United States and Western Europe. In National Institute of Mental Health Task Force on Homosexuality: Final Report mid Background Papers, J. Livingood, ed. DHEW Publication (HMS) 72-9116. Washington, DC: US Department of Health, Education, and Welfare, 22-29.
Gough, H.G. 1966. A cross-cultural analysis of the CPI femininity scale. J. Consult. Psychol. 30:136-141.
Gough, H.G., K. Chun, and Y.E. Chung. 1968. Validation of the CPI femininity scale in Korea. Psvchol. Rep. 22:155-160.
Green, R. 1987. The "Sissy Boy Svndrorne" and the Development of Homosexuality. New Haven, CT: Yale University Press.
Hall, J.A.Y., and D. Kimura. 1995. Sexual orientation and performance on sexually dimorphic motor tasks. Arch. Sex. Behav. 24:395-407.
Hamer, D., and P. Copeland. 1994. The Science of Desire: The Search for the Gav Gene and the Biology of Behavior. New York: Simon and Schuster.
Hamer, D., S. Hu, V.L. Magnuson et al. 1993. A linkage between DNA markers on the X chromosome and male sexual orientation. Science 261:321-327.
Herdt, G., ed. 1994. Third Sex, Third Gender: Beyond Sexual Dimorphism in Culture and Historv. New York: Zone Books.
Heston, L.L., and J. Shields. 1968. Homosexuality in twins: A family study and a registry study. Arch. Gen. Psvrhiatr. 18:149-160.
Hirschfeld, M. 1936. Homosexuality. In Encyclopaedia Sexualis: A Comprehensive Encvclopaedia/Dictionarp of the Sexual Sciences, V. Robinson, ed. New York: Dingwall-Rock, 321-334.
Howard, R.C., F.J. Longmore, P.A. Mason et al. 1994. Contingent negative variation (CNV) and erotic preference in self-declared homosexuals and in child sex offenders. Biol. Psvchol. 38: l 69- t 81.
Hu, S., A. Pattatucci, C. Patterson et al. 1995. Linkage between sexual orientation and chromosome Xg28 in males but not in females. Natur. Genet. 11:248-256.
Kallmann, F.J. 1952. Twin and sibship: Study of overt male homosexuality. Am. J. Hum. Genet. 4:136-146.
Kennedy. H. 1988. Ulrichs: The Life and Works of Karl Heinrich Ulrichs, Pioneer of the Modern Gav Rights Movement. Boston, MA: Alyson Publications.
King. M., and E. McDonald. 1992. Homosexuals who are twins: A study of 46 probands. Br. J. Psvchiatr. 160:40709.
Kinsey, A.C., W.B. Pomeroy, and C.E. Martin. 1948. Sexual Behavior in the Human Male. Philadelphia, PA: W.B. Saunders.
Kinsey, A.C., W.B. Pomeroy, C.E. Martin et al. 1953. Sexual Behavior in the Human Female. Philadelphia, PA: W.B. Saunders.
Kirsch, J.A.W., and J.D. Weinrich. 1991. Homosexuality, nature, and biology: Is homosexuality natural? Does it matter? In Homosexuality: Research Implications for Public Policy, J.C. Gonsiorek and J.D. Weinrich, eds.
Newbury Park, CA: Sage Publications, 13-31.
Klein, F., B. Sepkoff, and T.J. Wolf. 1985. Sexual orientation: A multivariable dynamic process. J. Homosex. 11:35-50.
Kohl, J.V. 1995. The Scent of Eros: Mysteries of Odor in Human Sexuality. New York: Continuum Publishing.
Laumann, E., J. Gagnon. R. Michael et al. 1994. The Social Organization of Sexuality: Sexual Practices in the United States. Chicago, IL: University of Chicago Press.
LeVay, S. 1991. A difference in hypothalamic structure between heterosexual and homosexual men. Science 253:1034-1037.
Lovejoy, C.O. 1981. The origin of man. Science 211:341-350.
Maclntyre, F., and K.W. Estep. 1993. Sperm competition and the persistence of genes for male homosexuality. BiosN-stems 31:223-233.
Miner, M.H., M.A. West, and D.M. Day. 1995. Sexual preference for child and aggressive stimuli: Comparison of rapists and child molesters using auditory and visual stimuli. Behav. Res. Ther. 33:545-551.
Moran, P.A.P. 1972. Familial effects in schizophrenia and homosexuality. Aust. N.Z. J. Psychiatr. 6:116-119,
Neale, M.C. 1991. Statistical Modeling Using MX. Richmond, VA: Medical College of Virginia, Virginia Commonwealth University.
Packer. C.. D.A. Gilbert. and A.E. Pusey. 1991. A molecular genetic analysis of kinship and cooperation in African lions. Nature 351:562-564.
Pattatucci, A.M.L. 1998. Molecular investigations into complex behavior: Lessons from sexual orientation studies. Hum. Biol. 70(2):367-386 (this issue).
Pattatucci. A.M.L., and D.H. Hamer. 1995. Development and familiality of sexual orientation in females. Behan, Genet. 25:407-420.
Phillips, G., and R. Over. 1995. Differences between heterosexual, bisexual, and lesbian women in recalled childhood experiences. Arch. Sex. Behav. 24:1-20.
Pillard, R.C. 1990. The Kinsey scale: Is it familial? In HotnoserualitNlHetero.re.eualih-: Concepts of Sexual Orientation, D.P. McWhirter, S.A. Sanders, and J.M. Reinisch, eds. New York: Oxford University Press, 88-100.
Pillard, R.C. 1991. Masculinity and femininity in homosexuality: "Inversion" revisited. In Homosexuality: Research Implications for Public Policy, J. Gonsiorek and J.D. Weinrich, eds. Newbury Park, CA: Sage Publications, 32-43.
Pillard, R.C., and J.D. Weinrich. 1986. Evidence of familial nature of male homosexuality. Arch. Gen. Psvchiatr. 43:808-812.
Pillard. R.C., and J.D. Weinrich. 1987. The periodic table model of gender transpositions. 1. A theory based on masculinization and defeminization of the brain. J. Sex Res. 23:425-454.
Pillard. R.C.. J. Poumadere, and R.A. Carretta. 198 L Is homosexuality familial? A review, some data, and a suggestion. Arch. Sex. Behav. 10:465-475.
Pillard, R.C.. J.1. Poumadere, and R.A. Carretta. 1982. A family study of sexual orientation. Arch. Sex. Behav. 11:511-520.
Plomin. R., J.C. DeFries, and G.E. McClearn. 1990. Behavioral Genetics: A Primer. New York: W.H. Freeman.
Plomin, R., M.J. Owen, and P. McGuffin. 1994. The genetic basis of complex human behaviors. Science 264:1733-1739.
Reite. M., J. Sheeder, D. Richardson et al. 1995. Cerebral laterality in homosexual males: Preliminary communication using magnetoencephalography. Arch. Sex. Behav. 24:585-593.
Rogers, S., and C. Turner. 1991. Male-male sexual contact in the USA: Findings from five sample surveys, 1970-1990. J. Sex Res. 28:491-519.
Salais, D., and R.B. Fischer. 1995. Sexual preference and altruism. J. Homosex. 28:185-196-Seidman, S.N., and R.O. Rieder. 1994. A review of sexual behavior in the United States. Am. J. Psvchiatr. 151:330-341.
Sell, R.L.. J.A. Wells, and D. Wypij. 1995. The prevalence of homosexual behavior and attraction in the United States, the United Kingdom, and France: Results of national population-based samples. Arch. Sex. Behan. 24:235-248.
Smith, C. 1974. Concordance in
and interpretation. Am. J. Hum. Genet. 26:454-466.
Stringer. P., and T. Grygier. 1976. Male homosexuality, psychiatric patient status, and psycho-logical masculinity and femininity. Arch. Sex. Behav. 5:15-27.
Swaab, D.F., and M.A. Hoffman. 1990. An enlarged suprachiasmatic nucleus in homosexual men. Brain Res. 537:141-148.
Symons, D. 1979. The Evolution of Human Sexuality. New York: Oxford University Press. Terman, L.A., and C. Miles. 1936. Sex and Personality: Studies in Masculinity and Femininity. New York: McGraw-Hill.
Trivers. R.L. 1971. The evolution of reciprocal altruism. Q. Rev. Biol. 46:35-57.
Ulrichs, K.H. 1994. The Riddle of "Man-Mani ' v" Love: The Pioneering Work on Male Homosexualin, M.A. Lombardi-Nash, trans. Buffalo, NY: Prometheus Books.
Vasey, P.L. 1995. Homosexual behavior in primates: A review of evidence and theory. Int. I Primatol. 16:173-204.
von Krafft-Ebing, R. 1901. Psi chopathia Sexualis, 3d ed., translation of I Oth German ed. Chicago, IL: W.T. Keener.
Weinrich, J.D. 1987. Sexual Landscapes. New York: Scribner's.
Whitam. F.L. 1983. Culturally invariable properties of male homosexuality: Tentative conclusions from cross-cultural research. Arch. Sex. Behar. 22:207-226.
Whitam, F.L., and R.M. Mathy.
cross-gender behavior of homosexual females
Whitam, F.L., M.
and J. Martin. 1993. Homosexual orientation in twins: A report of
Zucker. K., J. Wild, S. Bradley
1993. Physical attractiveness of boys with gender identity disorder.
Sex. Behar. 22:23-36.