Essential Nutrients-Mood: Research Article
Treatment of Mood Lability and Explosive Rage with Minerals and Vitamins
|CITATION: Kaplan, B. J., Crawford,
S.G., et al. (2002) Treatment
of Mood Lability and Explosive Rage
with Minerals and Vitamins: Two Case Studies in Children Journal
of Child and Adolescent Psychopharmacology. Volume
12, Number 3, 2002 Pp. 205–219.
ABSTRACT: A micronutrient supplement containing a broad range of dietary minerals and vitamins is being examined for the treatment of mood lability in both adults and children (Kaplan et al. 2001; Popper 2001). To participate, the child simply had to exhibit mood lability, irritability, uncontrollable temper outbursts, or aggression. During pilot work, two medication-free boys with mood lability and explosive rage were studied in an open-label treatment followed by reversal and retreatment.
One child was an 8-year-old with atypical obsessive-compulsive disorder, and the other was a 12-year-old with pervasive developmental delay. Both boys were monitored using the mood and temper items from the Conners Parent Rating Scale, as well as the Child Behavior Checklist.
In addition, the boy with atypical obsessive-compulsive disorder was monitored with the child version of the Yale-Brown Obsessive Compulsive Scale. Both boys benefited from the micronutrient supplement when examined in ABAB designs: mood, angry outbursts, and obsessional symptoms improved when initially treated, returned when not taking the supplement, and remitted when the micronutrient supplement was reintroduced.Both boys have been followed and are stable on the nutritional supplement for over 2 years. These cases suggest that mood lability and explosive rage can, in some cases, be managed with a mixture of biologically active minerals and vitamins, without using lithium or other traditional psychopharmacologic agents.
TABLE 1 Ingredients of E.M. Power
Note: Treatment began with 32 capsules/day; maintenance dose was 8 capsules/day.
There is currently a proprietary blend, for which daily values are not established: dl-phenylalanine, glutamine (as l-glutamine), citrus bioflavonoids (from peel), grape seed (Vitis vinitera), choline (as choline bitartrate), inositol, Ginkgo biloba (from leaf), methionine (as l-methionine), germanium (as Germanium sesquioxide), boron (as boron amino acid chelate), vanadium (as vanadium amino acid chelate, vanadium complexa), and nickel (as nickel amino acid chelate, nickel complexa). Other ingredients include gelatin, magnesium stearate, microcrystalline cellulose, and silicon dioxide. Manufactured for The Synergy Group of Canada, by Evince International, Farmington, Utah. RDA = recommended daily allowance.
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