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Occult Thyroid Dysfunction in Patients With Refractory Depression
   
CITATION:  Gewirtz, G.R., Malaspina, D., et al. (1988). Occult Thyroid Dysfunction in Patients With Refractory Depression. Am J Psychiatry 145:1012-1014.     

ABSTRACT:  Assessment of metabolic rate was useful in evaluating refractory depression in six of 15 women. Five of the six had normal levels of T3 and T4; however, each had an elevated thyrotropin-stimulating hormone level or a low metabolic rate. The depressions responded to medication with thyroid hormone. 

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